Sec Form 4 Filing - Romness Paul A. @ OS Therapies Inc - 2025-02-28

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Romness Paul A. 2. Issuer Name and Ticker or Trading Symbol OS Therapies Inc [ OSTX] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director X __ 10% Owner X __ Officer (give title below) _____ Other (specify below) President and CEO (Last) (First) (Middle) C/O SHORE ACCOUNTANTS MD INC., 115 PULLMAN CROSSING ROAD, SUITE 103 3. Date of Earliest Transaction (MM/DD/YY) 02/28/2025 (Street) GRASONVILLE, MD21638 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock, par value $0.001 per share 02/28/2025 J 225,000 A $ 0 ( 1 ) 2,473,000 D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Romness Paul A. C/O SHORE ACCOUNTANTS MD INC. 115 PULLMAN CROSSING ROAD, SUITE 103 GRASONVILLE, MD21638 X X President and CEO Signatures /s/ Paul A. Romness 02/28/2025 Signature of Reporting Person Date

Explanation of Responses:

( 1 )Pursuant to a Transfer Agreement, effective as of May 13, 2024 (the "Transfer Agreement"), between Einodmil LLC ("Einodmil") and the reporting person, 600,000 shares of the issuer's common stock owned by the reporting person were placed in escrow in exchange for Einodmil's participation in a pre-IPO lock-up agreement. The Transfer Agreement, entered into in connection with the issuer's initial public offering, outlined conditions for distributing the 600,000 shares after expiration of the lock-up period, based on the 20-day VWAP of the issuer's common stock. On February 28, 2025, 225,000 of these shares were released from escrow and transferred to the reporting person. The remaining 375,000 shares were released from escrow and transferred to Einodmil.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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