Sec Form 4 Filing - Xilas Andrew @ STERIS plc - 2021-06-02

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Xilas Andrew 2. Issuer Name and Ticker or Trading Symbol STERIS plc [ STE] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) SVP and GM, Dental (Last) (First) (Middle) C/O 70 SIR JOHN ROGERSON'S QUAY 3. Date of Earliest Transaction (MM/DD/YY) 06/02/2021 (Street) DUBLIN, L22 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Ordinary Shares 06/02/2021 A 232 A 232 D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Restricted Stock Units ( 2 ) 06/02/2021 A 619 ( 2 ) ( 2 ) Ordinary Shares 619 ( 2 ) 619 D Restricted Stock Units ( 3 ) 06/02/2021 A 277 ( 3 ) ( 3 ) Ordinary Shares 277 ( 3 ) 976 D Restricted Stock Units ( 4 ) 06/02/2021 A 1,445 ( 4 ) ( 4 ) Ordinary Shares 1,445 ( 4 ) 2,421 D Restricted Stock Units ( 5 ) 06/02/2021 A 999 ( 5 ) ( 5 ) Ordinary Shares 999 ( 5 ) 3,420 D Restricted Stock Units ( 6 ) 06/02/2021 A 113 ( 6 ) ( 6 ) Ordinary Shares 113 ( 6 ) 3,533 D Restricted Stock Units ( 7 ) 06/02/2021 A 373 ( 7 ) ( 7 ) Ordinary Shares 373 ( 7 ) 3,906 ( 8 ) D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Xilas Andrew C/O 70 SIR JOHN ROGERSON'S QUAY DUBLIN, L22 SVP and GM, Dental Signatures /s/ Ronald E. Snyder, Authorized Representative under Power of Attorney 06/04/2021 Signature of Reporting Person Date

Explanation of Responses:

( 1 )Received in exchange for 687 shares of Cantel Medical Corp. ("Cantel") common stock in connection with the acquisition of Cantel by STERIS plc ("STERIS") pursuant to a series of transactions (the "Mergers"). Holders of Cantel common stock received $16.93 in cash and 0.33787 STERIS ordinary shares ("Ordinary Shares") per Cantel share outstanding immediately prior to the Mergers. ( 2 )Reflects 619 restricted stock units ("RSUs") of STERIS. Each STERIS RSU represents a right to receive one Ordinary Share. These STERIS RSUs were received in exchange for 1,453 RSUs of Cantel in connection with the Mergers based on an exchange ratio of 0.4262 STERIS RSUs for every Cantel RSU outstanding immediately prior to the Mergers, with the number of resulting STERIS RSUs rounded to the nearest whole unit. These RSUs are restricted and vest in two equal installments on 10/10/2021 and 10/10/2022. ( 3 )Reflects 277 STERIS RSUs. Each STERIS RSU represents a right to receive one Ordinary Share. These STERIS RSUs were received in exchange for 650 Cantel RSUs in connection with the Mergers based on an exchange ratio of 0.4262 STERIS RSUs for every Cantel RSU outstanding immediately prior to the Mergers, with the number of resulting STERIS RSUs rounded to the nearest whole unit. These RSUs are restricted and vest in two equal installments on 10/10/2021 and 10/10/2022. ( 4 )Reflects 1,445 STERIS RSUs. Each STERIS RSU represents a right to receive one Ordinary Share. These STERIS RSUs were received in exchange for 3,390 Cantel RSUs in connection with the Mergers based on an exchange ratio of 0.4262 STERIS RSUs for every Cantel RSU outstanding immediately prior to the Mergers, with the number of resulting STERIS RSUs rounded to the nearest whole unit. These RSUs are restricted and vest in three equal installments on 10/7/2021, 10/7/2022 and 10/7/2023. ( 5 )Reflects 999 STERIS RSUs. Each STERIS RSU represents a right to receive one Ordinary Share. These STERIS RSUs were received in exchange for 2,345 Cantel RSUs in connection with the Mergers based on an exchange ratio of 0.4262 STERIS RSUs for every Cantel RSU outstanding immediately prior to the Mergers, with the number of resulting STERIS RSUs rounded to the nearest whole unit. These RSUs are restricted and vest in three equal installments on 12/2/2021, 12/2/2022 and 12/2/2023. ( 6 )Reflects 113 STERIS RSUs. Each STERIS RSU represents a right to receive one Ordinary Share. These STERIS RSUs were received in exchange for 265 performance-based restricted stock units ("PSUs") of Cantel in connection with the Mergers based on an exchange ratio of 0.4262 STERIS RSUs for every Cantel PSU outstanding immediately prior to the Mergers, with the number of resulting STERIS RSUs rounded to the nearest whole unit. These RSUs are restricted and vest in equal installments on 10/10/2021 and 10/10/2022. ( 7 )Reflects 373 STERIS RSUs. Each STERIS RSU represents a right to receive one Ordinary Share. These STERIS RSUs were received in exchange for 875 Cantel PSUs in connection with the Mergers based on an exchange ratio of 0.4262 STERIS RSUs for every Cantel PSU outstanding immediately prior to the Mergers, with the number of resulting STERIS RSUs rounded to the nearest whole unit. These RSUs are restricted and vest in equal installments on 10/7/2021, 10/7/2022 and 10/7/2023. ( 8 )The STERIS RSUs will vest as follows: 607 on October 7, 2021, 506 on October 10, 2021, 333 on December 2, 2021, 606 on October 7, 2022, 503 on October 10, 2022, 333 on December 2, 2022, 605 on October 7, 2023 and 333 on December 2, 2023.

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