Sec Form 4 Filing - SHAW DAVID E @ Schrodinger, Inc. - 2021-04-19

Insider filing report for Changes in Beneficial Ownership
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FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP
Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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1. Name and Address of Reporting Person
SHAW DAVID E
 2. Issuer Name and Ticker or Trading Symbol
Schrodinger, Inc. [ SDGR] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director X __ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last) (First) (Middle)
120 WEST 45TH STREET, 39TH FLOOR 		3. Date of Earliest Transaction (MM/DD/YY)
04/19/2021
(Street)
NEW YORK, NY10036 		4. If Amendment, Date Original Filed (MM/DD/YY)
6. Individual or Joint/Group Filing (Check Applicable Line)
_____ Form filed by One Reporting Person
__ X __ Form filed by More than One Reporting Person
(City) (State) (Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4) 		7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock, par value $0.01 per share 04/19/2021 S( 1 ) 12,345 D $ 72.873 ( 2 ) 7,942,060 I Held by Schrodinger Equity Holdings, LLC ( 3 )
Common Stock, par value $0.01 per share 04/19/2021 S( 1 ) 7,904 D $ 73.698 ( 4 ) 7,934,156 I Held by Schrodinger Equity Holdings, LLC ( 3 )
Common Stock, par value $0.01 per share 04/19/2021 S( 1 ) 3,261 D $ 75.0601 ( 5 ) 7,930,895 I Held by Schrodinger Equity Holdings, LLC ( 3 )
Common Stock, par value $0.01 per share 04/19/2021 S( 1 ) 3,280 D $ 76.3555 ( 6 ) 7,927,615 I Held by Schrodinger Equity Holdings, LLC ( 3 )
Common Stock, par value $0.01 per share 04/19/2021 S( 1 ) 3,210 D $ 76.8295 ( 7 ) 7,924,405 I Held by Schrodinger Equity Holdings, LLC ( 3 )
Common Stock, par value $0.01 per share 04/20/2021 S( 1 ) 16,966 D $ 70.0342 ( 8 ) 7,907,439 I Held by Schrodinger Equity Holdings, LLC ( 3 )
Common Stock, par value $0.01 per share 04/20/2021 S( 1 ) 5,420 D $ 70.698 ( 9 ) 7,902,019 I Held by Schrodinger Equity Holdings, LLC ( 3 )
Common Stock, par value $0.01 per share 04/20/2021 S( 1 ) 7,014 D $ 71.7291 ( 10 ) 7,895,005 I Held by Schrodinger Equity Holdings, LLC ( 3 )
Common Stock, par value $0.01 per share 04/20/2021 S( 1 ) 600 D $ 72.4202 ( 11 ) 7,894,405 I Held by Schrodinger Equity Holdings, LLC ( 3 )
Common Stock, par value $0.01 per share 04/21/2021 S( 1 ) 2,850 D $ 69.5088 ( 12 ) 7,891,555 I Held by Schrodinger Equity Holdings, LLC ( 3 )
Common Stock, par value $0.01 per share 04/21/2021 S( 1 ) 1,927 D $ 70.3325 ( 13 ) 7,889,628 I Held by Schrodinger Equity Holdings, LLC ( 3 )
Common Stock, par value $0.01 per share 04/21/2021 S( 1 ) 11,931 D $ 71.6937 ( 14 ) 7,877,697 I Held by Schrodinger Equity Holdings, LLC ( 3 )
Common Stock, par value $0.01 per share 04/21/2021 S( 1 ) 13,292 D $ 72.4051 ( 15 ) 7,864,405 I Held by Schrodinger Equity Holdings, LLC ( 3 )
Common Stock, par value $0.01 per share 4,264 I Held by D. E. Shaw Technology Development, LLC ( 16 )
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3) 		2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code
(Instr. 8) 		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5) 		6. Date Exercisable and Expiration Date
(MM/DD/YY) 		7. Title and Amount of Underlying Securities
(Instr. 3 and 4) 		8. Price of Derivative Security
(Instr. 5) 		9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4) 		10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4) 		11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Reporting Owners
Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
SHAW DAVID E
120 WEST 45TH STREET, 39TH FLOOR
NEW YORK, NY10036		 X
Schrodinger Equity Holdings, LLC
120 WEST 45TH STREET, 39TH FLOOR
NEW YORK, NY10036		 X
Signatures
David E. Shaw, By: /s/ Charles Ardai, as Attorney-in-Fact for David E. Shaw 04/21/2021
Signature of Reporting Person Date
Schrodinger Equity Holdings, LLC, By: /s/ Charles Ardai, Authorized Signatory 04/21/2021
Signature of Reporting Person Date
Explanation of Responses: ( 1 )The transactions reported in this line of this Form 4 were effected pursuant to a Rule 10b5-1 sales plan dated August 13, 2020.
( 2 )This is a weighted average sale price for the transactions reported on this line. Sales ranged in price from $72.35 to $73.34, inclusive. The Reporting Person undertakes to provide upon request by the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.
( 3 )Schrodinger Equity Holdings, LLC, which holds these securities, is owned in its entirety through a trust of which David E. Shaw is the trustee and beneficiary.
( 4 )This is a weighted average sale price for the transactions reported on this line. Sales ranged in price from $73.35 to $74.20, inclusive. The Reporting Person undertakes to provide upon request by the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.
( 5 )This is a weighted average sale price for the transactions reported on this line. Sales ranged in price from $74.64 to $75.50, inclusive. The Reporting Person undertakes to provide upon request by the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.
( 6 )This is a weighted average sale price for the transactions reported on this line. Sales ranged in price from $75.69 to $76.64, inclusive. The Reporting Person undertakes to provide upon request by the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.
( 7 )This is a weighted average sale price for the transactions reported on this line. Sales ranged in price from $76.69 to $77.015, inclusive. The Reporting Person undertakes to provide upon request by the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.
( 8 )This is a weighted average sale price for the transactions reported on this line. Sales ranged in price from $69.315 to $70.31, inclusive. The Reporting Person undertakes to provide upon request by the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.
( 9 )This is a weighted average sale price for the transactions reported on this line. Sales ranged in price from $70.315 to $71.31, inclusive. The Reporting Person undertakes to provide upon request by the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.
( 10 )This is a weighted average sale price for the transactions reported on this line. Sales ranged in price from $71.315 to $72.305, inclusive. The Reporting Person undertakes to provide upon request by the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.
( 11 )This is a weighted average sale price for the transactions reported on this line. Sales ranged in price from $72.32 to $72.55, inclusive. The Reporting Person undertakes to provide upon request by the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.
( 12 )This is a weighted average sale price for the transactions reported on this line. Sales ranged in price from $68.92 to $69.875, inclusive. The Reporting Person undertakes to provide upon request by the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.
( 13 )This is a weighted average sale price for the transactions reported on this line. Sales ranged in price from $69.92 to $70.69, inclusive. The Reporting Person undertakes to provide upon request by the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.
( 14 )This is a weighted average sale price for the transactions reported on this line. Sales ranged in price from $71.09 to $72.08, inclusive. The Reporting Person undertakes to provide upon request by the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.
( 15 )This is a weighted average sale price for the transactions reported on this line. Sales ranged in price from $72.10 to $72.91, inclusive. The Reporting Person undertakes to provide upon request by the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.
( 16 )David E. Shaw is President and sole shareholder of D. E. Shaw & Co. II, Inc., which is the sole member of D. E. Shaw Technology Development, LLC.

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